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Time to stratify? The retinoblastoma protein in castrate-resistant prostate cancer

It is generally held that the retinoblastoma (RB) tumor suppressor functions in multiple tissues to protect against tumor development. However, preclinical studies and analysis of tumor samples of early disease did not support an important role of RB loss in the origin of prostate cancer. By contras...

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Bibliografiske detaljer
Main Authors: Aparicio, Ana, Den, Robert B., Knudsen, Karen E.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641817/
https://ncbi.nlm.nih.gov/pubmed/21811228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrurol.2011.107
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