Slug increases sensitivity to tubulin-binding agents via the downregulation of βIII and βIVa-tubulin in lung cancer cells

Transcription factor Slug/SNAI2 (snail homolog 2) plays a key role in the induction of the epithelial mesenchymal transition in cancer cells; however, whether the overexpression of Slug mediates the malignant phenotype and alters drug sensitivity in lung cancer cells remains largely unclear. We inve...

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Main Authors: Tamura, Daisuke, Arao, Tokuzo, Nagai, Tomoyuki, Kaneda, Hiroyasu, Aomatsu, Keiichi, Fujita, Yoshihiko, Matsumoto, Kazuko, De Velasco, Marco A, Kato, Hiroaki, Hayashi, Hidetoshi, Yoshida, Shuhei, Kimura, Hideharu, Maniwa, Yoshimasa, Nishio, Wataru, Sakai, Yasuhiro, Ohbayashi, Chiho, Kotani, Yoshikazu, Nishimura, Yoshihiro, Nishio, Kazuto
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2013
Assuntos:
Cancer Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639653/
https://ncbi.nlm.nih.gov/pubmed/23634282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.68
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