Active Component of Danshen (Salvia miltiorrhiza Bunge), Tanshinone I, Attenuates Lung Tumorigenesis via Inhibitions of VEGF, Cyclin A, and Cyclin B Expressions

Tanshinone I (T1) and tanshinone II (T2) are the major diterpenes isolated from Danshen (Salvia miltiorrhiza Bunge). Three human lung adenocarcinoma cell lines, A549, CL1-0, and CL1-5, were treated with T1 and T2 for the in vitro antitumor test. Results showed that T1 was more effective than T2 in i...

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Main Authors: Tung, Yu-Tang, Chen, Hsiao-Ling, Lee, Cheng-Yu, Chou, Yu-Ching, Lee, Po-Ying, Tsai, Hsin-Chung, Lin, Yi-Ling, Chen, Chuan-Mu
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638627/
https://ncbi.nlm.nih.gov/pubmed/23662128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/319247
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