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Brain-Derived Neurotrophic Factor Signaling and Subgenual Anterior Cingulate Cortex Dysfunction in Major Depressive Disorder

OBJECTIVE: The subgenual anterior cingulate cortex is implicated in the pathology and treatment response of major depressive disorder. Low levels of brain-derived neurotrophic factor (BDNF) and reduced markers for GABA function, including in the amygdala, are reported in major depression, but their...

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Main Authors: Tripp, Adam, Oh, Hyunjung, Guilloux, Jean-Philippe, Martinowich, Keri, Lewis, David A., Sibille, Etienne
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638149/
https://ncbi.nlm.nih.gov/pubmed/23128924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2012.12020248
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