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CDK4: A Key Player in the Cell Cycle, Development, and Cancer

The cell cycle is regulated in part by cyclins and their associated serine/threonine cyclin-dependent kinases, or CDKs. CDK4, in conjunction with the D-type cyclins, mediates progression through the G(1) phase when the cell prepares to initiate DNA synthesis. Although CDK4-null mutant mice are viabl...

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Bibliografiske detaljer
Main Authors: Baker, Stacey J., Reddy, E. Premkumar
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636745/
https://ncbi.nlm.nih.gov/pubmed/23634254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601913478972
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