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TGF β1 induces apoptosis in invasive prostate cancer and bladder cancer cells via Akt-independent, p38 MAPK and JNK/SAPK-mediated activation of caspases

Recent findings indicate that advanced stage cancers shun the tumor suppressive actions of TGFβ and inexplicably utilize the cytokine as a tumor promoter. We investigated the effect of TGFβ1 on the survival and proliferation of invasive prostate (PC3) and bladder (T24) cancer cells. Our study indica...

詳細記述

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書誌詳細
主要な著者: Al-Azayzih, Ahmad, Gao, Fei, Goc, Anna, Somanath, Payaningal R.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635477/
https://ncbi.nlm.nih.gov/pubmed/22989755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.09.035
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