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Zoom zoom: racing CARs for multiple myeloma

Chimeric antigen receptors re-direct T cells to surface antigens. Discovery and validation of appropriate target antigens expands the possible indications for CAR-T cells. BCMA is expressed only on mature B cells and plasma cells and promotes their survival. BCMA is a promising target for CAR-T cell...

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Bibliographic Details
Main Authors: Maus, Marcela V., June, Carl H.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630266/
https://ncbi.nlm.nih.gov/pubmed/23444214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0168
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