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The NRTIs Lamivudine, Stavudine and Zidovudine Have Reduced HIV-1 Inhibitory Activity in Astrocytes
HIV-1 establishes infection in astrocytes and macroage-lineage cells of the central nervous system (CNS). Certain antiretroviral drugs (ARVs) can penetrate the CNS, and are therefore often used in neurologically active combined antiretroviral therapy (Neuro-cART) regimens, but their relative activit...
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Główni autorzy: | , , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
Public Library of Science
2013
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3628669/ https://ncbi.nlm.nih.gov/pubmed/23614033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062196 |
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