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In Vivo Expansion of Co-Transplanted T Cells Impacts on Tumor Re-Initiating Activity of Human Acute Myeloid Leukemia in NSG Mice

Human cells from acute myeloid leukemia (AML) patients are frequently transplanted into immune-compromised mouse strains to provide an in vivo environment for studies on the biology of the disease. Since frequencies of leukemia re-initiating cells are low and a unique cell surface phenotype that inc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: von Bonin, Malte, Wermke, Martin, Cosgun, Kadriye Nehir, Thiede, Christian, Bornhauser, Martin, Wagemaker, Gerard, Waskow, Claudia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621959/
https://ncbi.nlm.nih.gov/pubmed/23585844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060680
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