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The Pharmaco –, Population and Evolutionary Dynamics of Multi-drug Therapy: Experiments with S. aureus and E. coli and Computer Simulations

There are both pharmacodynamic and evolutionary reasons to use multiple rather than single antibiotics to treat bacterial infections; in combination antibiotics can be more effective in killing target bacteria as well as in preventing the emergence of resistance. Nevertheless, with few exceptions li...

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Библиографические подробности
Главные авторы: Ankomah, Peter, Johnson, Paul J. T., Levin, Bruce R.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617031/
https://ncbi.nlm.nih.gov/pubmed/23593006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003300
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