Up-Regulation of RACK1 by TGF-β1 Promotes Hepatic Fibrosis in Mice

Liver fibrosis represents the consequences of a sustained wound healing response to chronic liver injury, and activation of quiescent hepatic stellate cells (HSCs) into a myofibroblast-like phenotype is considered as the central event of liver fibrosis. RACK1, the receptor for activated C-kinase 1,...

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Bibliographic Details
Main Authors: Jia, Dongwei, Duan, Fangfang, Peng, Peike, Sun, Linlin, Liu, Xiaojuan, Wang, Lan, Wu, Weicheng, Ruan, Yuanyuan, Gu, Jianxin
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612079/
https://ncbi.nlm.nih.gov/pubmed/23555900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060115
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