Stromal Targeting of Sodium Iodide Symporter Using Mesenchymal Stem Cells Allows Enhanced Imaging and Therapy of Hepatocellular Carcinoma

The tumor-homing property of mesenchymal stem cells (MSC) has lead to their use as delivery vehicles for therapeutic genes. The application of the sodium iodide symporter (NIS) as therapy gene allows noninvasive imaging of functional transgene expression by (123)I-scintigraphy or PET-imaging, as wel...

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Detalhes bibliográficos
Main Authors: Knoop, Kerstin, Schwenk, Nathalie, Dolp, Patrick, Willhauck, Michael J., Zischek, Christoph, Zach, Christian, Hacker, Markus, Göke, Burkhard, Wagner, Ernst, Nelson, Peter J., Spitzweg, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609610/
https://ncbi.nlm.nih.gov/pubmed/23402366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.104
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