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The Enterovirus 71 A-particle Forms a Gateway to Allow Genome Release: A CryoEM Study of Picornavirus Uncoating

Since its discovery in 1969, enterovirus 71 (EV71) has emerged as a serious worldwide health threat. This human pathogen of the picornavirus family causes hand, foot, and mouth disease, and also has the capacity to invade the central nervous system to cause severe disease and death. Upon binding to...

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Bibliographic Details
Main Authors: Shingler, Kristin L., Yoder, Jennifer L., Carnegie, Michael S., Ashley, Robert E., Makhov, Alexander M., Conway, James F., Hafenstein, Susan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605244/
https://ncbi.nlm.nih.gov/pubmed/23555253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003240
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