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Promoter-Specific Transcription Inhibition in Staphylococcus aureus by a Phage Protein
Phage G1 gp67 is a 23 kDa protein that binds to the Staphylococcus aureus (Sau) RNA polymerase (RNAP) σ(A) subunit and blocks cell growth by inhibiting transcription. We show that gp67 has little to no effect on transcription from most promoters but is a potent inhibitor of ribosomal RNA transcripti...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3604623/ https://ncbi.nlm.nih.gov/pubmed/23178120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.10.034 |
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