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Effective anti-neu initiated anti-tumor responses require the complex role of CD4(+) T cells

PURPOSE: Targeting oncogenic receptors with antibodies has been thought to suppress tumor growth mainly by interrupting oncogenic signals. Recently, the essential role for adaptive immunity, and CD8(+) T cells in particular, has been established as a major factor for anti-HER2/neu mediated tumor reg...

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Hlavní autoři: Mortenson, Eric D., Park, SaeGwang, Jiang, Zhujun, Wang, Shengdian, Fu, Yang-Xin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602165/
https://ncbi.nlm.nih.gov/pubmed/23363817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2522
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