Endogenous ovarian hormones affect mitochondrial efficiency in cerebral endothelium via distinct regulation of PGC-1 isoforms

Mitochondria support the energy-intensive functions of brain endothelium but also produce damaging-free radicals that lead to disease. Previously, we found that estrogen treatment protects cerebrovascular mitochondria, increasing capacity for ATP production while decreasing reactive oxygen species (...

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Detaylı Bibliyografya
Asıl Yazarlar: Kemper, Martin F, Zhao, Yuanzi, Duckles, Sue P, Krause, Diana N
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2013
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597365/
https://ncbi.nlm.nih.gov/pubmed/23093066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.159
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