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Human intestinal transporter database: QSAR modeling and virtual profiling of drug uptake, efflux and interactions

PURPOSE: Membrane transporters mediate many biological effects of chemicals and play a major role in pharmacokinetics and drug resistance. The selection of viable drug candidates among biologically active compounds requires the assessment of their transporter interaction profiles. METHODS: Using pub...

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Detaylı Bibliyografya
Asıl Yazarlar: Sedykh, Alexander, Fourches, Denis, Duan, Jianmin, Hucke, Oliver, Garneau, Michel, Zhu, Hao, Bonneau, Pierre, Tropsha, Alexander
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596480/
https://ncbi.nlm.nih.gov/pubmed/23269503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0935-x
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