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Human intestinal transporter database: QSAR modeling and virtual profiling of drug uptake, efflux and interactions
PURPOSE: Membrane transporters mediate many biological effects of chemicals and play a major role in pharmacokinetics and drug resistance. The selection of viable drug candidates among biologically active compounds requires the assessment of their transporter interaction profiles. METHODS: Using pub...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3596480/ https://ncbi.nlm.nih.gov/pubmed/23269503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0935-x |
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