State-of-the-Art Fusion-Finder Algorithms Sensitivity and Specificity

Background. Gene fusions arising from chromosomal translocations have been implicated in cancer. RNA-seq has the potential to discover such rearrangements generating functional proteins (chimera/fusion). Recently, many methods for chimeras detection have been published. However, specificity and sens...

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Main Authors: Carrara, Matteo, Beccuti, Marco, Lazzarato, Fulvio, Cavallo, Federica, Cordero, Francesca, Donatelli, Susanna, Calogero, Raffaele A.
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595110/
https://ncbi.nlm.nih.gov/pubmed/23555082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/340620
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