Proteins binding to 5' untranslated region sites: a general mechanism for translational regulation of mRNAs in human and yeast cells.

We demonstrate that a bacteriophage protein and a spliceosomal protein can be converted into eukaryotic translational repressor proteins. mRNAs with binding sites for the bacteriophage MS2 coat protein or the spliceosomal human U1A protein were expressed in human HeLa cells and yeast. The presence o...

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Dettagli Bibliografici
Autori principali: Stripecke, R, Oliveira, C C, McCarthy, J E, Hentze, M W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC359116/
https://ncbi.nlm.nih.gov/pubmed/8065323
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