The Transcription Factors Tbx18 and Wt1 Control the Epicardial Epithelial-Mesenchymal Transition through Bi-Directional Regulation of Slug in Murine Primary Epicardial Cells

During cardiac development, a subpopulation of epicardial cells migrates into the heart as part of the epicardial epithelial-mesenchymal transition (EMT) and differentiates into smooth muscle cells and fibroblasts. However, the roles of transcription factors in the epicardial EMT are poorly understo...

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Main Authors: Takeichi, Makiko, Nimura, Keisuke, Mori, Masaki, Nakagami, Hironori, Kaneda, Yasufumi
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585213/
https://ncbi.nlm.nih.gov/pubmed/23469079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057829
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