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Challenges in Detecting Magnesium Stearate Distribution in Tablets

Magnesium stearate (MS) is the most commonly used lubricant in pharmaceutical industry. During blending, MS particles form a thin layer on the surfaces of the excipient and drug particles prohibiting the bonding from forming between the particles. This hydrophobic layer decreases the tensile strengt...

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Autores principales: Lakio, Satu, Vajna, Balázs, Farkas, István, Salokangas, Henri, Marosi, György, Yliruusi, Jouko
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581680/
https://ncbi.nlm.nih.gov/pubmed/23378252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-013-9927-3
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