Identification of DEAD-box RNA Helicase 6 (DDX6) as a Cellular Modulator of Vascular Endothelial Growth Factor Expression under Hypoxia

Vascular endothelial growth factor A (VEGF) is a crucial proangiogenic factor, which regulates blood vessel supply under physiologic and pathologic conditions. The VEGF mRNA 5′-untranslated region (5′-UTR) bears internal ribosome entry sites (IRES), which confer sustained VEGF mRNA translation under...

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Bibliographische Detailangaben
Hauptverfasser: de Vries, Sebastian, Naarmann-de Vries, Isabel S., Urlaub, Henning, Lue, Hongqi, Bernhagen, Jürgen, Ostareck, Dirk H., Ostareck-Lederer, Antje
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581395/
https://ncbi.nlm.nih.gov/pubmed/23293030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.420711
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