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UCP2 Deficiency Helps to Restrict the Pathogenesis of Experimental Cutaneous and Visceral Leishmaniosis in Mice

BACKGROUND: Uncoupling protein 2 (UCP2) is a mitochondrial transporter that has been shown to lower the production of reactive oxygen species (ROS). Intracellular pathogens such as Leishmania upregulate UCP2 and thereby suppress ROS production in infected host tissues, allowing the multiplication of...

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Main Authors: Carrión, Javier, Abengozar, M. Angeles, Fernández-Reyes, María, Sánchez-Martín, Carlos, Rial, Eduardo, Domínguez-Bernal, Gustavo, González-Barroso, M. Mar
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578745/
https://ncbi.nlm.nih.gov/pubmed/23437414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002077
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