An Extract of Artemisia dracunculus L. Inhibits Ubiquitin-Proteasome Activity and Preserves Skeletal Muscle Mass in a Murine Model of Diabetes

Impaired insulin signaling is a key feature of type 2 diabetes and is associated with increased ubiquitin-proteasome-dependent protein degradation in skeletal muscle. An extract of Artemisia dracunculus L. (termed PMI5011) improves insulin action by increasing insulin signaling in skeletal muscle. W...

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Main Authors: Kirk-Ballard, Heather, Wang, Zhong Q., Acharya, Priyanka, Zhang, Xian H., Yu, Yongmei, Kilroy, Gail, Ribnicky, David, Cefalu, William T., Floyd, Z. Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577785/
https://ncbi.nlm.nih.gov/pubmed/23437325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057112
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