Paraptosis and NF-κB activation are associated with protopanaxadiol-induced cancer chemoprevention

BACKGROUND: Protopanaxadiol (PPD) is a triterpenoid that can be prepared from steamed ginseng. PPD possesses anticancer potential via caspase-dependent apoptosis. Whether paraptosis, a type of the caspase-independent cell death, is also induced by PPD has not been evaluated. METHODS: Cell death, the...

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Bibliographic Details
Main Authors: Wang, Chong-Zhi, Li, Binghui, Wen, Xiao-Dong, Zhang, Zhiyu, Yu, Chunhao, Calway, Tyler D, He, Tong-Chuan, Du, Wei, Yuan, Chun-Su
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575249/
https://ncbi.nlm.nih.gov/pubmed/23281928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-13-2
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