Tumor platinum concentration following intraperitoneal administration of cisplatin versus carboplatin in an ovarian cancer model

OBJECTIVE: Current intraperitoneal (IP) regimens for the treatment of ovarian cancer rely on cisplatin (DDP) whereas intravenous regimens rely on carboplatin (CBDCA). A major question in the field is whether CBDCA can replace DDP for IP treatment. We compared the uptake of IP administered DDP and CB...

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Autors principals: Jandial, Danielle D., Messer, Karen, Farshchi-Heydari, Salman, Pu, Minya, Howell, Stephen B.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571663/
https://ncbi.nlm.nih.gov/pubmed/19775736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2009.08.028
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