GABP transcription factor is required for development of chronic myelogenous leukemia via its control of PRKD2

Hematopoietic stem cells (HSCs) are the source of all blood lineages, and HSCs must balance quiescence, self-renewal, and differentiation to meet lifelong needs for blood cell development. Transformation of HSCs by the breakpoint cluster region-ABL tyrosine kinase (BCR-ABL) oncogene causes chronic m...

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Detalhes bibliográficos
Main Authors: Yang, Zhong-Fa, Zhang, Haojian, Ma, Leyuan, Peng, Cong, Chen, Yaoyu, Wang, Junling, Green, Michael R., Li, Shaoguang, Rosmarin, Alan G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568343/
https://ncbi.nlm.nih.gov/pubmed/23345428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212904110
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