Identification of BfmR, a Response Regulator Involved in Biofilm Development, as a Target for a 2-Aminoimidazole-Based Anti-Biofilm Agent

2-aminoimidazoles (2AIs) have been documented to disrupt bacterial protection mechanisms, including biofilm formation and genetically-encoded antibiotic resistance traits. Using Acinetobacter baumannii, we provide initial insight into the mechanism of action of a 2AI-based antibiofilm agent. Confoca...

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Bibliographic Details
Main Authors: Thompson, Richele J., Bobay, Benjamin G., Stowe, Sean D., Olson, Andrew L., Peng, Lingling, Su, Zhaoming, Actis, Luis A., Melander, Christian, Cavanagh, John
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567222/
https://ncbi.nlm.nih.gov/pubmed/23186243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3015289
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