Presence of Terminal EPIYA Phosphorylation Motifs in Helicobacter pylori CagA Contributes to IL-8 Secretion, Irrespective of the Number of Repeats

CagA protein contributes to pro-inflammatory responses during H. pylori infection, following its intracellular delivery to gastric epithelial cells. Here, we report for the first time in an isogenic background, on the subtle role of CagA phosphorylation on terminal EPIYA-C motifs in the transcriptio...

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Main Authors: Papadakos, Konstantinos S., Sougleri, Ioanna S., Mentis, Andreas F., Hatziloukas, Efstathios, Sgouras, Dionyssios N.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567036/
https://ncbi.nlm.nih.gov/pubmed/23409168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056291
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