Presence of Terminal EPIYA Phosphorylation Motifs in Helicobacter pylori CagA Contributes to IL-8 Secretion, Irrespective of the Number of Repeats

CagA protein contributes to pro-inflammatory responses during H. pylori infection, following its intracellular delivery to gastric epithelial cells. Here, we report for the first time in an isogenic background, on the subtle role of CagA phosphorylation on terminal EPIYA-C motifs in the transcriptio...

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Bibliographic Details
Main Authors: Papadakos, Konstantinos S., Sougleri, Ioanna S., Mentis, Andreas F., Hatziloukas, Efstathios, Sgouras, Dionyssios N.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567036/
https://ncbi.nlm.nih.gov/pubmed/23409168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056291
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