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CPMV-DOX Delivers

The plant virus, Cowpea mosaic virus (CPMV), is developed as a carrier of the chemotherapeutic drug doxorubicin (DOX). CPMV-DOX conjugate, in which eighty DOX molecules are covalently bound to external surface carboxylates of the viral nanoparticle (VNP), shows greater cytotoxicity than free DOX tow...

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Detalhes bibliográficos
Main Authors: Aljabali, Alaa A.A., Shukla, Sourabh, Lomonossoff, George P., Steinmetz, Nicole F., Evans, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564650/
https://ncbi.nlm.nih.gov/pubmed/22827473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp3002057
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