Lipopolysaccharides with Acylation Defects Potentiate TLR4 Signaling and Shape T Cell Responses

Lipopolysaccharides or endotoxins are components of Gram-negative enterobacteria that cause septic shock in mammals. However, a LPS carrying hexa-acyl lipid A moieties is highly endotoxic compared to a tetra-acyl LPS and the latter has been considered as an antagonist of hexa-acyl LPS-mediated TLR4...

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Bibliografische gegevens
Hoofdauteurs: Martirosyan, Anna, Ohne, Yoichiro, Degos, Clara, Gorvel, Laurent, Moriyón, Ignacio, Oh, Sangkon, Gorvel, Jean-Pierre
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563657/
https://ncbi.nlm.nih.gov/pubmed/23390517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055117
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