Novel Loci Associated with PR Interval in a Genome-Wide Association Study of Ten African American Cohorts

BACKGROUND: The PR interval (PR) as measured by the resting, standard 12-lead electrocardiogram (ECG) reflects the duration of atrial/atrioventricular nodal depolarization. Substantial evidence exists for a genetic contribution to PR, including genome-wide association studies that have identified co...

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Main Authors: Butler, Anne M., Yin, Xiaoyan, Evans, Daniel S., Nalls, Michael A., Smith, Erin N., Tanaka, Toshiko, Li, Guo, Buxbaum, Sarah G., Whitsel, Eric A., Alonso, Alvaro, Arking, Dan E., Benjamin, Emelia J., Berenson, Gerald S., Bis, Josh C., Chen, Wei, Deo, Rajat, Ellinor, Patrick T., Heckbert, Susan R., Heiss, Gerardo, Hsueh, Wen-Chi, Keating, Brendan J., Kerr, Kathleen F., Li, Yun, Limacher, Marian C., Liu, Yongmei, Lubitz, Steven A., Marciante, Kristin D., Mehra, Reena, Meng, Yan A., Newman, Anne B., Newton-Cheh, Christopher, North, Kari E., Palmer, Cameron D., Psaty, Bruce M., Quibrera, P. Miguel, Redline, Susan, Reiner, Alex P., Rotter, Jerome I., Schnabel, Renate B., Schork, Nicholas J., Singleton, Andrew B., Smith, J. Gustav, Soliman, Elsayed Z., Srinivasan, Sathanur R., Zhang, Zhu-ming, Zonderman, Alan B., Ferrucci, Luigi, Murray, Sarah S., Evans, Michele K., Sotoodehnia, Nona, Magnani, Jared W., Avery, Christy L.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560365/
https://ncbi.nlm.nih.gov/pubmed/23139255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.112.963991
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