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Does the lipid environment impact the open-state conductance of an engineered β-barrel protein nanopore?

Using rational membrane protein design, we were recently able to obtain a β-barrel protein nanopore that was robust under an unusually broad range of experimental circumstances. This protein nanopore was based upon the native scaffold of the bacterial ferric hydroxamate uptake component A (FhuA) of...

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Autors principals: Tomita, Noriko, Mohammad, Mohammad M., Niedzwiecki, David J., Ohta, Makoto, Movileanu, Liviu
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560310/
https://ncbi.nlm.nih.gov/pubmed/23246446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2012.12.003
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