Inherited Variants in Regulatory T Cell Genes and Outcome of Ovarian Cancer

Although ovarian cancer is the most lethal of gynecologic malignancies, wide variation in outcome following conventional therapy continues to exist. The presence of tumor-infiltrating regulatory T cells (Tregs) has a role in outcome of this disease, and a growing body of data supports the existence...

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Autores principales: Goode, Ellen L., DeRycke, Melissa, Kalli, Kimberly R., Oberg, Ann L., Cunningham, Julie M., Maurer, Matthew J., Fridley, Brooke L., Armasu, Sebastian M., Serie, Daniel J., Ramar, Priya, Goergen, Krista, Vierkant, Robert A., Rider, David N., Sicotte, Hugues, Wang, Chen, Winterhoff, Boris, Phelan, Catherine M., Schildkraut, Joellen M., Weber, Rachel P., Iversen, Ed, Berchuck, Andrew, Sutphen, Rebecca, Birrer, Michael J., Hampras, Shalaka, Preus, Leah, Gayther, Simon A., Ramus, Susan J., Wentzensen, Nicolas, Yang, Hannah P., Garcia-Closas, Montserrat, Song, Honglin, Tyrer, Jonathan, Pharoah, Paul P. D., Konecny, Gottfried, Sellers, Thomas A., Ness, Roberta B., Sucheston, Lara E., Odunsi, Kunle, Hartmann, Lynn C., Moysich, Kirsten B., Knutson, Keith L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559692/
https://ncbi.nlm.nih.gov/pubmed/23382860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053903
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