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Inherited Variants in Regulatory T Cell Genes and Outcome of Ovarian Cancer

Although ovarian cancer is the most lethal of gynecologic malignancies, wide variation in outcome following conventional therapy continues to exist. The presence of tumor-infiltrating regulatory T cells (Tregs) has a role in outcome of this disease, and a growing body of data supports the existence...

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Autors principals: Goode, Ellen L., DeRycke, Melissa, Kalli, Kimberly R., Oberg, Ann L., Cunningham, Julie M., Maurer, Matthew J., Fridley, Brooke L., Armasu, Sebastian M., Serie, Daniel J., Ramar, Priya, Goergen, Krista, Vierkant, Robert A., Rider, David N., Sicotte, Hugues, Wang, Chen, Winterhoff, Boris, Phelan, Catherine M., Schildkraut, Joellen M., Weber, Rachel P., Iversen, Ed, Berchuck, Andrew, Sutphen, Rebecca, Birrer, Michael J., Hampras, Shalaka, Preus, Leah, Gayther, Simon A., Ramus, Susan J., Wentzensen, Nicolas, Yang, Hannah P., Garcia-Closas, Montserrat, Song, Honglin, Tyrer, Jonathan, Pharoah, Paul P. D., Konecny, Gottfried, Sellers, Thomas A., Ness, Roberta B., Sucheston, Lara E., Odunsi, Kunle, Hartmann, Lynn C., Moysich, Kirsten B., Knutson, Keith L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559692/
https://ncbi.nlm.nih.gov/pubmed/23382860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053903
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