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Atherosclerotic geometries exacerbate pathological thrombus formation poststenosis in a von Willebrand factor-dependent manner

Rupture of a vulnerable atherosclerotic plaque causes thrombus formation and precipitates cardiovascular diseases. In addition to the thrombogenic content of a plaque, also the hemodynamic microenvironment plays a major role in thrombus formation. How the altered hemodynamics around a plaque promote...

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Detalhes bibliográficos
Main Authors: Westein, Erik, van der Meer, Andries D., Kuijpers, Marijke J. E., Frimat, Jean-Philippe, van den Berg, Albert, Heemskerk, Johan W. M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557050/
https://ncbi.nlm.nih.gov/pubmed/23288905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209905110
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