Effect of obesity reduction on preservation of heart function and attenuation of left ventricular remodeling, oxidative stress and inflammation in obese mice

BACKGROUND: Obesity is an important cardiovascular risk factor. This study tested the effect of obesity reduction on preserving left ventricular ejection fraction (LVEF) and attenuating inflammation, oxidative stress and LV remodeling in obese mice. METHODS AND RESULTS: Eight-week-old C57BL/6 J mice...

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Main Authors: Wang, Hui-Ting, Liu, Chu-Feng, Tsai, Tzu-Hsien, Chen, Yung-Lung, Chang, Hsueh-Wen, Tsai, Ching-Yen, Leu, Steve, Zhen, Yen-Yi, Chai, Han-Tan, Chung, Sheng-Ying, Chua, Sarah, Yen, Chia-Hung, Yip, Hon-Kan
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551744/
https://ncbi.nlm.nih.gov/pubmed/22784636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-145
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