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Centrosomal MPF triggers the mitotic and morphogenetic switches of fission yeast
Activation of mitosis promoting factor (MPF) drives mitotic commitment(1). In human cells active MPF appears first on centrosomes(2). We show that local activation of MPF on the equivalent organelle of fission yeast, the spindle pole body (SPB), promotes Polo kinase activity at the SPBs long before...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549529/ https://ncbi.nlm.nih.gov/pubmed/23222840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2633 |
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