Centrosomal MPF triggers the mitotic and morphogenetic switches of fission yeast

Activation of mitosis promoting factor (MPF) drives mitotic commitment(1). In human cells active MPF appears first on centrosomes(2). We show that local activation of MPF on the equivalent organelle of fission yeast, the spindle pole body (SPB), promotes Polo kinase activity at the SPBs long before...

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Bibliographic Details
Main Authors:	Grallert, Agnes, Patel, Avinash, Tallada, Victor A., Chan, Kuan Yoow, Bagley, Steven, Krapp, Andrea, Simanis, Viesturs, Hagan, Iain M
Format:	Artigo
Language:	Inglês
Published:	2012
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3549529/ https://ncbi.nlm.nih.gov/pubmed/23222840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2633
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Centrosomal MPF triggers the mitotic and morphogenetic switches of fission yeast

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