Polymorphisms in the Gene Regions of the Adaptor Complex LAMTOR2/LAMTOR3 and Their Association with Breast Cancer Risk

BACKGROUND: The late endosomal LAMTOR complex serves as a convergence point for both the RAF/MEK/ERK and the PI3K/AKT/mTOR pathways. Interestingly, both of these signalling cascades play a significant role in the aetiology of breast cancer. Our aim was to address the possible role of genetic polymor...

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Asıl Yazarlar: De Araujo, Mariana E., Erhart, Gertraud, Buck, Katharina, Müller-Holzner, Elisabeth, Hubalek, Michael, Fiegl, Heidelinde, Campa, Daniele, Canzian, Federico, Eilber, Ursula, Chang-Claude, Jenny, Coassin, Stefan, Haun, Margot, Kedenko, Lyudmyla, Paulweber, Bernhard, Reitsamer, Roland, Himmel, Irmgard, Flesch-Janys, Dieter, Lamina, Claudia, Kronenberg, Florian, Huber, Lukas A., Kloss-Brandstätter, Anita
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547070/
https://ncbi.nlm.nih.gov/pubmed/23341997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053768
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