Acute Inactivation of PSD-95 Destabilizes AMPA Receptors at Hippocampal Synapses

Postsynatptic density protein (PSD-95) is a 95 kDa scaffolding protein that assembles signaling complexes at synapses. Over-expression of PSD-95 in primary hippocampal neurons selectively increases synaptic localization of AMPA receptors; however, mice lacking PSD-95 display grossly normal glutamate...

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Bibliographic Details
Main Authors: Yudowski, Guillermo A., Olsen, Olav, Adesnik, Hillel, Marek, Kurt W., Bredt, David S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546964/
https://ncbi.nlm.nih.gov/pubmed/23342049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053965
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