A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data

Motivation: The Illumina Infinium 450 k DNA Methylation Beadchip is a prime candidate technology for Epigenome-Wide Association Studies (EWAS). However, a difficulty associated with these beadarrays is that probes come in two different designs, characterized by widely different DNA methylation distr...

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Autors principals: Teschendorff, Andrew E., Marabita, Francesco, Lechner, Matthias, Bartlett, Thomas, Tegner, Jesper, Gomez-Cabrero, David, Beck, Stephan
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Original Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546795/
https://ncbi.nlm.nih.gov/pubmed/23175756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts680
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