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Rheumatoid arthritis is associated with signaling alterations in naturally occurring autoreactive B-lymphocytes
Immune tolerance established during the development of B lymphocytes can be subverted in mature cells and lead to autoimmunity. This study focuses on the recently discovered subset of CD19(+)CD27(−)IgD(+)IgM(low/−) B cells that recognize self-antigens and have the capacity to produce autoantibodies,...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3546227/ https://ncbi.nlm.nih.gov/pubmed/23058039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2012.09.001 |
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