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Nifedipine prevents etoposide-induced caspase-3 activation, prenyl transferase degradation and loss in cell viability in pancreatic β-cells

Emerging evidence implicates novel roles for post-translational prenylation [i.e., farnesylation and geranylgeranylation] of various signaling proteins in a variety of cellular functions including hormone secretion, survival and apoptosis. In the context of cellular apoptosis, it has been shown prev...

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Detalhes bibliográficos
Main Authors: Arora, Daleep K., Mohammed, Abiy M., Kowluru, Anjaneyulu
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545074/
https://ncbi.nlm.nih.gov/pubmed/23054080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-012-0763-9
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