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A Monte Carlo-based framework enhances the discovery and interpretation of regulatory sequence motifs

BACKGROUND: Discovery of functionally significant short, statistically overrepresented subsequence patterns (motifs) in a set of sequences is a challenging problem in bioinformatics. Oftentimes, not all sequences in the set contain a motif. These non-motif-containing sequences complicate the algorit...

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Autori principali: Seitzer, Phillip, Wilbanks, Elizabeth G, Larsen, David J, Facciotti, Marc T
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542263/
https://ncbi.nlm.nih.gov/pubmed/23181585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-317
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