WRP/srGAP3 Facilitates the Initiation of Spine Development by an Inverse F-BAR Domain, and Its Loss Impairs Long-Term Memory

The WAVE-associated Rac GAP, WRP, is thought to regulate key aspects of synapse development and function and may be linked to mental retardation in humans. WRP contains a newly described inverse F-BAR (IF-BAR) domain of unknown function. Our studies show that this domain senses/facilitates outward p...

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Main Authors: Carlson, Benjamin R., Lloyd, Krissey E., Kruszewski, Allison, Kim, Il-Hwan, Rodriguiz, Ramona M., Heindel, Clifford, Faytell, Marika, Dudek, Serena M., Wetsel, William C., Soderling, Scott H.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541779/
https://ncbi.nlm.nih.gov/pubmed/21325512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4433-10.2011
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