A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis

Endometriosis is considered as an estrogen-dependent inflammatory disease but its etiology is unclear. To date, a mechanistic role for steroid receptor coactivators (SRCs) in endometriosis progression has not been elucidated. An SRC-1(−/−) mouse model reveals that the SRC-1 gene plays an essential r...

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Main Authors: Han, Sang Jun, Hawkins, Shannon M., Begum, Khurshida, Jung, Sung Yun, Kovanci, Ertug, Qin, Jun, Lydon, John P., DeMayo, Francesco J., O'Malley, Bert W.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541027/
https://ncbi.nlm.nih.gov/pubmed/22660634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2826
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