Triplex DNA-binding proteins are associated with clinical outcomes revealed by proteomic measurements in patients with colorectal cancer

BACKGROUND: Tri- and tetra-nucleotide repeats in mammalian genomes can induce formation of alternative non-B DNA structures such as triplexes and guanine (G)-quadruplexes. These structures can induce mutagenesis, chromosomal translocations and genomic instability. We wanted to determine if proteins...

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Bibliografiska uppgifter
Huvudupphovsmän: Nelson, Laura D, Bender, Christian, Mannsperger, Heiko, Buergy, Daniel, Kambakamba, Patryk, Mudduluru, Giridhar, Korf, Ulrike, Hughes, Dennis, Van Dyke, Michael W, Allgayer, Heike
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2012
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537547/
https://ncbi.nlm.nih.gov/pubmed/22682314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-38
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